Raldh1 promotes adiposity during adolescence independently of retinal signaling

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Raldh1 promotes adiposity during adolescence independently of retinal signaling

All-trans-retinoic acid (RA) inhibits adipogenesis in established preadipocyte cell lines. Dosing pharmacological amounts of RA reduces weight gain in mice fed a high-fat diet, i.e. counteracts diet-induced obesity (DIO). The aldehyde dehydrogenase Raldh1 (Aldh1a1) functions as one of three enzymes that converts the retinol metabolite retinal into RA, and one of many proteins that contribute to...

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Sleep duration and adiposity during adolescence.

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Sleep Duration and Adiposity During Adolescence

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Longitudinal changes in adiposity during adolescence: a population-based cohort

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2017

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0187669